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Vivek Sharma

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BIO

Vivek is a doctoral candidate affiliated with the Donders Centre for Neuroscience at Radboud University. Their research is centred on the investigation of the dynamic repertoire of the brain, with a specific focus on comprehending the mechanisms underlying post-stroke brain lesions and traumatic brain injuries.

 

Their research interests encompass the exploration of brain dynamics and functional connectomes, as well as the application of biophysical models for simulating brain activity. They employ graph theoretical measures and information theory to gain insights into the broader dynamics of the brain's systems.

 

Ultimately, Vivek aspires to translate this knowledge into innovative therapeutic approaches, such as transcranial ultrasound stimulation, aimed at reorganizing brain dynamics and expediting the recovery process. By precisely targeting pivotal brain nodes, their research holds the potential to enhance inter-regional communication, providing a ray of hope for individuals grappling with neurological disorders.

MY WORK

My work focuses on exploring the dynamic repertoire of the brain in different conditions, with a particular emphasis on understanding the mechanisms underlying post-stroke brain lesions or traumatic brain injury. My research is driven by the conviction that a better understanding of the brain's complex interactions and dynamics can lead to the development of more effective therapies for patients with neurological disorders.

To this end, I analyse electroencephalogram (EEG) and magnetoencephalogram (MEG) data from patients to gain insights into the functional connectivity of the brain in different states, such as resting or task performance. I use biophysical models of coupled oscillators to simulate the activity of neurons and synapses and uncover the underlying mechanisms of brain dynamics.

Moreover, I employ graph theoretical measures and information theory to further pinpoint the most crucial nodes and networks in the brain and to understand how they contribute to the overall dynamics of the system. By combining these tools, I aim to develop a comprehensive understanding of the complex interplay between different brain regions and how they contribute to healthy brain function.

Finally, I aim to translate this knowledge into innovative therapeutic strategies, such as transcranial ultrasound stimulation, to reorganize brain dynamics and accelerate recovery. By identifying and stimulating key nodes in the brain, we may be able to promote more efficient and effective communication between different regions, leading to better outcomes for patients with neurological disorders

CONTACT ME

Faculty of Science 

Department of Biophysics

Heyendaalseweg 135

6525 AJ Nijmegen

The Netherlands

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